Show Summary Details
Introduction to Bioinformatics

Introduction to Bioinformatics

Arthur M. Lesk
Page of

Printed from Oxford Science Trove. Under the terms of the licence agreement, an individual user may print out a single article for personal use (for details see Privacy Policy and Legal Notice).

date: 24 June 2024

1. Introductionlocked

1. Introductionlocked

  • Arthur M. LeskArthur M. LeskThe Pennsylvania State University


This introductory chapter presents the major components of bioinformatics: DNA and protein sequences and structures, genomes and proteomes, databases and information retrieval, the World Wide Web, and computer programming. Before the advent of modern technologies and the internet, biological observations were fundamentally anecdotal and fragmentary. In recent generations, the data have become not only much more quantitative, but also more precise and comprehensive. Biological databases have recently supplemented the archives of nucleic acid sequences, amino acid sequences of proteins, and structures of proteins and protein–nucleic acid complexes. Given the data streams, analysis has become ever more challenging. Not only has bioinformatics developed powerful tools, but its methods are becoming more deeply integrated into the biomedical enterprise.

You do not currently have access to this article


Please login to access the full content.


Access to the full content requires a subscription