p. 714. Intracellular Signals
- John T. HancockJohn T. HancockProfessor of Cell Signalling, University of the West of England, Bristol
Abstract
This chapter discusses the need for intracellular signalling and talks about signalling pathways that involve cAMP. It clarifies how G proteins are involved in signalling and can mediate disease. It also shows how cGMP is involved in signalling. It then highlights the use of inositol compounds in signalling and points out the importance of calcium ions in signalling events. The chapter focuses on the modulation of the concentration of molecules that are involved in relaying the message into and across the inner structures of the cell. It specifically explains how cyclic nucleotides, lipid-derived compounds, inositol-based compounds, calcium ions, and proteins are involved in mediating some of the signalling pathways.
