Molecular Biology of RNA (Second Edition)
Published in Print:12 November 2015 Published Online:31 August 2023
ISBN:9780199671397
Publisher:Oxford University Press
Abstract
Molecular Biology of RNA provides an overview of a cutting-edge field of biology. It starts with an introduction to the subject. It looks at how RNA can form versatile structures. It moves on to consider catalytic RNAs. Other topics covered include pre-mRNA splicing by the spliceosome, the RNA-binding proteins, pre-mRNA splicing defects found in development and disease, and co-transcriptional pre-mRNA processing. The text also looks at nucleocytoplasmic traffic of messenger RNA, messenger RNA localization, and translation of messenger RNA. It also examines stability and degradation of mRNA and RNA editing. Finally, the text provides an analysis on biogenesis and nucleocytoplasmic traffic of non-coding RNAs; the 'macro' RNAs, which include long non-coding RNAs and epigenetics; and the short non-coding RNAs and gene silencing. The text ends with a quick look at future perspectives.
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Contents
- Front Matter
- 1. Introduction to Molecular Biology of RNA
- 2. RNA can form versatile structures
- 3. Catalytic RNAs
- 4. The RNA-binding proteins
- 5. Pre-mRNA splicing by the spliceosome
- 6. Regulated alternative splicing
- 7. Pre-mRNA splicing defects in development and disease
- 8. Co-transcriptional pre-mRNA processing
- 9. Nucleocytoplasmic traffic of messenger RNA
- 10. Messenger RNA localization
- 11 Translation of messenger RNA
- 12 Stability and degradation of mRNA
- 13 RNA editing
- 14 The biogenesis and nucleocytoplasmic traffic of non-coding RNAs
- 15 The ‘macro’ RNAs: long non-coding RNAs and epigenetics
- 16 The short non-coding RNAs and gene silencing
- 17 RNA biology: future perspectives
- End Matter
© David Elliott and Michael Ladomery 2016
