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Cover Molecular Biology of RNA

David Elliott and Michael Ladomery

Molecular Biology of RNA provides an overview of a cutting-edge field of biology. It starts with an introduction to the subject. It looks at how RNA can form versatile structures. It moves on to consider catalytic RNAs. Other topics covered include pre-mRNA splicing by the spliceosome, the RNA-binding proteins, pre-mRNA splicing defects found in development and disease, and co-transcriptional pre-mRNA processing. The text also looks at nucleocytoplasmic traffic of messenger RNA, messenger RNA localization, and translation of messenger RNA. It also examines stability and degradation of mRNA and RNA editing. Finally, the text provides an analysis on biogenesis and nucleocytoplasmic traffic of non-coding RNAs; the 'macro' RNAs, which include long non-coding RNAs and epigenetics; and the short non-coding RNAs and gene silencing. The text ends with a quick look at future perspectives.