Molecular Biology of Cancer starts with an introduction. It then looks at the cancer genome. Other chapters consider the regulation of gene expression, growth factor signaling, and oncogenes. The cell cycle is also considered, as are tumor suppressor genes. The text moves on to look at apoptosis, cancer stem cells and the regulation of self-renewal and differentiation pathways. There are also chapters on metastasis, angiogenesis, reprogrammed metabolism and diet, tumor immunology and immunotherapy, and inflammation and infection. Finally, the text considers strategies and tools for research and for drug development.
