Concepts in Bioinformatics and Genomics starts with a review of molecular biology and looks at its relevance to the topic. It then goes on to consider information organization and sequence databases, molecular evolution, substitution matrices, and pairwise sequence alignment. Other topics covered include the basic local alignment sequence tool and multiple sequence alignment, protein structure prediction, phylogenetics, genomics, transcript and protein expression analysis, and basic probability. There are also chapters on advanced probability for bioinformatics applications, programming basics and applications to bioinformatics, and how to develop a basic bioinformatics tool.
Book
Jamil Momand, Alison McCurdy, Silvia Heubach, and Nancy Warter-Perez
Book
Arthur M. Lesk
Introduction to Bioinformatics starts off by introducing the topic. It then looks at genetics and genomes. It moves on to consider the panorama of life. The text also considers alignments and phylogenetic trees. There is a chapter on structural bioinformatics and drug discovery. The text also examines scientific publications and archives, particularly media, content, access, and presentation. Artificial intelligence is considered as well, in addition to machine learning. There is an introduction to systems biology that follows towards the end. The book's final chapters look at metabolic pathways and control of organization.
Book
Arthur M. Lesk
Introduction to Protein Science firstly outlines the topics ahead. The first main topic is protein structure and protein structure determination. The next subject the text considers is bioinformatics of protein sequence and structure. Proteins as catalysts is examined after that. This discussion particularly looks at enzyme structure, kinetics, and mechanisms. The text then moves on to describe proteins with partners, the evolution of protein structure and function, and protein folding and design. Finally, it looks at proteomics and systems biology.